Neuroscience/cellular illustration about microglia © 2020 Alisa Brandt

Microglial Activity

This illustration is intended to provide neuroscience students an overview of specialized brain cells called microglia, by distilling complex, growing research into a concise and memorable poster. A defining characteristic of microglia is their ability to transform dramatically and take on different shapes and functions to monitor the neuronal environment and respond quickly to problems. Two main states are depicted in this illustration: a highly-branched “surveying” form, and an “active”

Macular hole staging and surgical treatment illustration © 2019 Alisa Brandt

Macular Hole: Staging and Surgical Treatment

Illustration explaining stages in macular hole formation in the fovea and surgical treatment by peeling the internal limiting membrane during a vitrectomy procedure. Figure 1 and surgical instruments were first created in ZBrush or Cinema 4D, followed by painting in Photoshop. Designed to be a fold-out page in a scientific or medical journal. Created during the Ophthalmological Illustration course in the Medical and Biological Illustration graduate program at Johns Hopkins University

Left frontal craniotomy surgical illustration

Left Frontal Craniotomy for Tumor Resection

Illustration of a left frontal craniotomy to remove a large brain tumor, designed for slide presentation. Created during the Surgical Illustration course in the Medical and Biological Illustration graduate program at Johns Hopkins University School of Medicine.

3D render of instruments

3D Instruments

A retractor, scalpel, and electrocautery instrument modeled and rendered in Cinema 4D. Created during the Medical and Biological Illustration graduate program at Johns Hopkins University School of Medicine.

3D render of blood cells

Blood Cells

Red blood cells and a white blood cell modeled and rendered in Cinema 4D. Created during the Medical and Biological Illustration graduate program at Johns Hopkins University School of Medicine.

Molecular immunotherapy poster

Immunotherapy to Fight Cancer

Immune checkpoint blocking therapies, or ICBs, help fight cancer by inhibiting the down-regulation of effector T cell activity. Here, two CD8+ T cells (in blue) approach a cancer cell (in brown), while ICB antibodies flow in from the upper right to block interaction between PD-1 and PDL-1. Peptide fragments (in red) are being presented by the cancer cell on its surface in HLA-I (Human Leukocyte Antigen) molecules, which make up

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